ISSN 1307-1068 | E-ISSN 1308-5271
Original Article
Efficacy of Rapid Diagnostic Testing for Influenza in Reducing Laboratory Tests and Improving Patient Management in the Pediatric Emergency Department
1 Özel Ümit Hastanesi, Enfeksiyon Hastalıkları Kliniği, Eskişehir, Türkiye  
2 Dr. Behçet Uz Çocuk Hastalıkları ve Cerrahisi Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İzmir, Türkiye  
3 Özel Sante Plus Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, Türkiye  
4 Özel BSK Anadolu Hastanesi, Nöroloji Kliniği, Kütahya, Türkiye  
J Pediatr Inf 2010; 4: 65-70
DOI: 10.5152/ced.2010.04
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Key Words: Childhood, hepatitis A, complication

Objective: Hepatitis A virus infections are a widespread disease with important morbidity and mortality in adults. The aim of this study is to evaluate the clinical and laboratory findings, treatment and prognosis of the acute viral hepatitis A cases in our hospital.


Material and Method: IIn this study, 241 children diagnosed with acute viral hepatitis A were evaluated according to demographic and clinical characteristics between April 2007 and August 2008. 


Results: Of the patients, 134 (55.6%) were male and 107 (44.4%) were female, and the mean age of the patients was 7±5 years (range, 2-16). The incidence of hepatitis A was higher in autumn and winter. In 169 (70.1%) of the cases no route of transmission could be determined. The most common symptoms were jaundice (82.1%), weakness (80%), nausea (74.2%), anorexia (70.9%) and dark urine (68%). The most common signs were jaundice (94.2%), hepatomegaly (58.1%) and splenomegaly (21.6%). The total rate of hematological abnormalities was 43.1% and fulminant hepatitis was seen in 1.2% of the patients. The mortality rate was determined as 0.8%.


Conclusions: Hepatitis A remains an important public health problem in the country. The disease causes more severe clinical symptoms and requires rest during the epidemic in adults. Therefore, hepatitis A vaccination may be useful in early childhood in hyperendemic regions.

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