Efficacy of Rapid Diagnostic Testing for Influenza in Reducing Laboratory Tests and Improving Patient Management in the Pediatric Emergency Department
Özel Ümit Hastanesi, Enfeksiyon Hastalıkları Kliniği, Eskişehir, Türkiye
Dr. Behçet Uz Çocuk Hastalıkları ve Cerrahisi Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İzmir, Türkiye
Özel Sante Plus Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, Türkiye
Özel BSK Anadolu Hastanesi, Nöroloji Kliniği, Kütahya, Türkiye
J Pediatr Inf 2010; 4: 65-70
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Key Words: Childhood, hepatitis A, complication
Objective: Hepatitis A virus infections are a widespread disease with important morbidity and mortality in adults. The aim of this study is to evaluate the clinical and laboratory findings, treatment and prognosis of the acute viral hepatitis A cases in our hospital.
Material and Method: IIn this study, 241 children diagnosed with acute viral hepatitis A were evaluated according to demographic and clinical characteristics between April 2007 and August 2008.
Results: Of the patients, 134 (55.6%) were male and 107 (44.4%) were female, and the mean age of the patients was 7±5 years (range, 2-16). The incidence of hepatitis A was higher in autumn and winter. In 169 (70.1%) of the cases no route of transmission could be determined. The most common symptoms were jaundice (82.1%), weakness (80%), nausea (74.2%), anorexia (70.9%) and dark urine (68%). The most common signs were jaundice (94.2%), hepatomegaly (58.1%) and splenomegaly (21.6%). The total rate of hematological abnormalities was 43.1% and fulminant hepatitis was seen in 1.2% of the patients. The mortality rate was determined as 0.8%.
Conclusions: Hepatitis A remains an important public health problem in the country. The disease causes more severe clinical symptoms and requires rest during the epidemic in adults. Therefore, hepatitis A vaccination may be useful in early childhood in hyperendemic regions.